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Table 1 Updates to language/format items after analysis of existing guidance tools

From: The Guideline Language and Format Instrument (GLAFI): development process and international needs assessment survey

Subdomain (underlined)

Original content

Updated content

Source and justification

Language

CLEAR

actionable/effective writing

Action item:

Use words that convey the strength of recommendations (as per GRADE guidelines)

Action items:

If using the GRADE approach:

Identify recommendations according to their strength

Use an action verb corresponding to the strength of a recommendation to operationalize it

Employ consistent use of a letter, number, and/or symbol system for characterizing both the strength of a recommendation and the quality of evidence

Source: GRADE Handbook [13]

Justification: authors’ consensus

Language

CLEAR

consistent use of termsa

N/A

Action items:

Use the same semantic indicators (use the same terminology to indicate level of evidence, strength of recommendation, and the action verbs) across recommendations

When comparing alternative approaches, always frame the recommendations in favor of a particular management approach rather than against an alternative

Reserve use of “not” for recommendations against a management approach that may be particularly harmful and/or widespread

Source: IOM [9]

Justification: author consensus

Source: GRADE Handbook [13]

Justification: author consensus

Source: GRADE Handbook [13]

Justification: author consensus

Format

Presentation

document structure

Action item:

Ensure that the guideline has a clearly identifiable and optimal structure

Operational definition:

• Clear chunking (grouping) of information: Use sequential arrangement or bundling

• Ensure standardized usage of formatting indicators such as type sizes and weights (e.g., bold)

• Consider structuring by dividing patients into specific subclasses, if relevant

Action item:

Ensure that the guideline has a clearly identifiable and optimal structure

Operational definition:

- Newly added components:

• Group specific recommendations near the summary of key evidence for those recommendations

• Consider using bold and/or underline to draw attention to all recommendations, or, if applicable, to a subset of recommendations pertaining to the main PICO question(s) covered by the guideline

• Report recommendations in a way that is visible and easy to find (i.e. do not embed recommendations within long paragraphs, and consider grouping recommendations in a summary section).

Source: AGREE II [8]

Justification: authors’ consensus

Source: AGREE II [8], GLIA [3] Justification: found in more than one existing guidance document

Source: IOM [9], GUIDELINES 2.0 [11], AGREE II [8]

Justification: found in more than one existing guidance document

  1. aNewly added subdomain, defined as: Ensure that the same terms are used across recommendations whenever possible, and that these terms are used to consistently (i.e. to indicate the same meaning). Concepts within this subdomain were identified in 3 reference guidance documents: GRADE, IOM, Guidelines 2.0