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Table 1 Targeted barriers and content of 3HP delivery strategies

From: Protocol for the 3HP Options Trial: a hybrid type 3 implementation-effectiveness randomized trial of delivery strategies for short-course tuberculosis preventive therapy among people living with HIV in Uganda

Capability Opportunity Motivation Selected intervention function(s) Selected behavior change technique Selected
mode of delivery
Knowledge Capacity to remember Capacity to plan Time to access 3HP Cost to access 3HP Inadequate support Beliefs about consequences Self-efficacy Lack of cues/reminders    
Facilitated directly-observed therapy (DOT)
         Education, persuasion Information about health consequences Standardized counseling by clinic nurse
         Environmental restructuring Restructuring physical environment Streamlined weekly clinic visits + cost reimbursement
         Enablement Prompts/cues Appointment reminders via Interactive Voice Response (IVR)
       Education, persuasion Credible source Weekly visit with health worker (DOT)
Facilitated self-administered therapy (SAT)
         Education, persuasion Information about health consequences Standardized counseling by clinic nurse
         Environmental restructuring Restructuring physical environment SAT + streamlined monthly clinic visits + cost reimbursement
        Enablement Prompts/cues Dosing reminders and confirmation via IVR
          Enablement Social support Weekly check-in via IVR
Patient choice between facilitated DOT and facilitated SAT
       Education, enablement Problem solving Shared decision-making, facilitated by decision aid